Biological Function
A DNA topoisomerase I inhibitor.
Formal Name
1,11-dichloro-12,13-dihydro-12-(4-O-methyl-Beta-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione
Type
Rebeccamycin, BRN 4732638, NSC 359079
Classification
Biochemical, Chemical
Molecular Formula
C27H21Cl2N3O7
Molecular Weight
570.4 g/mol
Formulation
a lyophilisate
Solubility
Soluble in organic solvents such as DMSO and dimethyl formamide.
SMILES
O=C(NC1=O)C2=C1C(C(C=CC=C3Cl)=C3N4[C@]5([H])O[C@H](CO)[C@@H](OC)[C@H](O)[C@H]5O)=C4C6=C2C7=C(C(Cl)=CC=C7)N6
InChI Code
InChI=1S/C27H21Cl2N3O7/c1-38-24-13(8-33)39-27(23(35)22(24)34)32-20-10(5-3-7-12(20)29)15-17-16(25(36)31-26(17)37)14-9-4-2-6-11(28)18(9)30-19(14)21(15)32/h2-7,13,22-24,27,30,33-35H,8H2,1H3,(H,31,36,37)/t13-,22-,23-,24-,27-/m1/s1
InChI Key
QEHOIJJIZXRMAN-QZQSLCQPSA-N
Storage
Store at -20°C for up to 2 years.
Usage Information
Rebeccamycin is supplied as a lyophilisate. A stock solution may be made by dissolving the rebeccamycin in the solvent of choice. Rebeccamycin is soluble in organic solvents such as DMSO and dimethyl formamide, which should be purged with an inert gas.
Restrictions
For research use only.Available for shipment within the USA only
Guarantee
This Biochemical carries the LSBio 100% Guarantee