Lifespan/PathPlus™ GPER1 / GPR30 Antibody Extracellular Domain Polyclonal ELISA,IHC LS‑A4268/50 µg (1 mg/ml)/LS-A4268-50,Lifespan,,Lifespan,lsbio,LifeSpan BioSciences Inc.,Lifespan美元价/进货价 LSBio 2 PLD4/磷脂酶D4抗体,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Lifespan/PathPlus™ GPER1 / GPR30 Antibody Extracellular Domain Polyclonal ELISA,IHC LS‑A4268/50 µg (1 mg/ml)/LS-A4268-50

产品编号：LS-A4268-50

市场价：¥8500.00

场地：美国(厂家直采)

产品分类：抗体类>二抗>抗过氧化物酶>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$425.00

品牌： Lifespan

公司：LifeSpan BioSciences, Inc.

公司分类：

商品介绍

Description

G-proteincoupledestrogenreceptor1(GPER1)promotesneuritogenesisindevelopinghippocampalneurons.ItplaysaroleinacuteneuroprotectionagainstNMDA-inducedexcitotoxicneuronaldeathandincreasesfiringactivityandintracellularcalciumoscillationsinluteinizinghormone-releasinghormone(LHRH)neurons.GPER1inhibitsmatureADIpocytedifferentiationandlipidaccumulation,andisinvolvedintherecruitmentofbeta-arrestin2ARRB2attheplasmamembraneinepithelialcells.Italsofunctionsasareceptorforaldosterone,mediatingrapidregulationofvascularcontractibilitythroughthePI3K/ERKsignalingpathway.Finally,itisimplicatedincancerprogression.TheUniProtConsortium.NucleicAcidsRes.47:D506-515(2019);NucleicAcidsRes.2016Jan4;44(D1):D733-45,PMID:26553804

Target

HumanGPER1/GPR30

SeeAllGPER1/GPR30Antibodies

Host

Rabbit

Reactivity

Human(testedor100%immunogensequenceidentity)

Predicted

Monkey(atleast90%immunogensequenceidentity)

Clonality

Polyclonal

Conjugations

Unconjugated.AlsoavailableconjugatedwithAP,APC,Biotin,FITC,HRP,PE.

Purification

Immunoaffinitypurified

Modifications

Unmodified

Applications

IHC
IHC-Paraffin(5-7.5µg/ml)
ELISA
Applicationstestedforthebaseformofthisproductonly

PerformingIHC?SeeourcompletelineofImmunohistochemistryReagentsincludingantigenretrievalsolutions,blockingagentsABCDetectionKitsandpolymers,biotinylatedsecondaryantibodies,substratesandmore.

Immunogen

Synthetic15aminoacidpeptidefrom2ndextracellulardomainofhumanGPR30.PercentidentitywithotherspeciesbyBLASTanalysis:Human,Gorilla,Monkey(100%);Marmoset,Elephant(93%);Mouse,Rat,Hamster,Panda,Horse,Opossum,Platypus(87%);Dog,Bovine,Turkey,Zebrafinch,Chicken(80%).

BlockingPeptide

LS-E28930-Liquid-50µg-$145.00ImmunizingpeptideusedtogenerateLS-A4268.Usefulforpre-absorptionandneutralizationoftheantibody'santigenbindingsite.

Epitope

ExtracellularDomain

Specificity

HumanGPR30.BLASTanalysisofthepeptideimmunogenshowednohomologywithotherhumanproteins.

Presentation

PBS,0.1%SodiumAzide

Storage

Aliquotandstoreundilutedat-20°Corbelowforupto1year.Canbestoredundilutedat4°Cforupto1month.Avoidfreeze-thawcycles.

Restrictions

Forresearchuseonly.

Guarantee

ThisantibodycarriestheLSBIo100%Guarantee.

LSBioGuarantee

AboutGPER1/GPR30

Uniprot:Q99527NCBI:NM_001505NP_001496.1

品牌介绍

LifeSpan Biosciences（LSBio）公司成立于1995年，经过近20年的不断创新与发展.公司已成为生物分子病理学行业的领头羊，其主要产品包括抗体。免疫组化服务以及蛋白质定位数据库等；LSbio在高通量成像和癌症鉴别软件产品中也处于＊＊地位，公司正在开发用于在临诊前期和癌症诊断方面进行病理学解读的仪器和软件;LSBio的客户包括位于美国、欧洲和日本的超过100家制药公司。

公司介绍

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产品分类

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