Lifespan/PathPlus™ GLP1R / GLP‑1 Receptor Antibody N‑Terminus Polyclonal IF,IHC LS‑A1206/50 µg (1 mg/ml)/LS-A1206-50,Lifespan,,Lifespan,lsbio,LifeSpan BioSciences Inc.,抗FN1/纤连蛋白抗体LS-C43576 | LifeSpan Biosciences lifespan公司,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Lifespan/PathPlus™ GLP1R / GLP‑1 Receptor Antibody N‑Terminus Polyclonal IF,IHC LS‑A1206/50 µg (1 mg/ml)/LS-A1206-50

产品编号：LS-A1206-50

市场价：¥8500.00

场地：美国(厂家直采)

产品分类：抗体类>二抗>抗荧光素>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$425.00

品牌： Lifespan

公司：LifeSpan BioSciences, Inc.

公司分类：

商品介绍

Description

Glucagon-likepeptide1receptor(GLP1R)isareceptorforglucagonandglucagon-likepeptide-1(GLP1).Itisinvolvedininsulinsynthesisandrelease,bloodglucosehomeostasis,appetitecontrol,memoryandlearning,aswellascontrolofbreathingandheartrate.StimulationofGLP1Rbyendogenoushormoneinducesmultiplecomplementarymechanisms,whichtogetherresultinaloweringofcirculatingbloodglucoselevels.DesensitizationofGLP1Ronpancreaticbeta-cellsisoneofthecausesofnoninsulin-dependentdiabetesmellitus(NIDDM).Inimmunohistochemistry,GLP1Rhashighestmembranouspositivityonpancreaticbetacells,itisexpressedonneuronsinthebrainandnervoussystem,anditisalsofoundinthestomach,salivarygland,heartmuscle,gallbladder,salivarygland,duodenumandatlowlevelsinafewothertissues.TheUniProtConsortium.NucleicAcidsRes.47:D506-515(2019);NucleicAcidsRes.2016Jan4;44(D1):D733-45,PMID:26553804

(5)Publication(s)

Target

HumanGLP1R/GLP-1Receptor

SeeAllGLP1R/GLP-1ReceptorAntibodies

Host

Rabbit

Reactivity

Human,Mouse(testedor100%immunogensequenceidentity)

Predicted

Monkey,Mouse,Rat,Bovine,Hamster,Pig,Rabbit,Sheep(atleast90%immunogensequenceidentity)

Clonality

Polyclonal

Conjugations

Unconjugated.AlsoavailableconjugatedwithAP,APC,Biotin,FITC,HRP,PE.

Purification

Immunoaffinitypurified

Modifications

Unmodified

Applications

IHC
IHC-Paraffin(3-4µg/ml)
IHC-Frozen
Immunofluorescence
Applicationstestedforthebaseformofthisproductonly

PerformingIHC?SeeourcompletelineofImmunohistochemistryReagentsincludingantigenretrievalsolutions,blockingagentsABCDetectionKitsandpolymers,biotinylatedsecondaryantibodies,substratesandmore.

Immunogen

Synthetic16aminoacidpeptidefromN-TerminusextracellulardomainofhumanGLP1R.PercentidentitywithotherspeciesbyBLASTanalysis:Human,Gorilla,Gibbon,Monkey(100%);Marmoset,Mouse,Rat,Sheep,Bovine,Hamster,Elephant,Rabbit,Pig(94%).

Epitope

N-Terminus

Specificity

HumanGLP1R.BLASTanalysisofthepeptideimmunogenshowednohomologywithotherhumanproteins.

Presentation

PBS,0.1%SodiumAzide

Storage

Aliquotandstoreundilutedat-20°Corbelowforupto1year.Canbestoredundilutedat4°Cforupto1month.Avoidfreeze-thawcycles.

Restrictions

Forresearchuseonly.

Guarantee

ThisantibodycarriestheLSBIo100%Guarantee.

LSBioGuarantee

AboutGLP1R/GLP-1Receptor

Uniprot:P43220NCBI:NM_002062NP_002053.3

品牌介绍

LifeSpan Biosciences（LSBio）公司成立于1995年，经过近20年的不断创新与发展.公司已成为生物分子病理学行业的领头羊，其主要产品包括抗体。免疫组化服务以及蛋白质定位数据库等；LSbio在高通量成像和癌症鉴别软件产品中也处于＊＊地位，公司正在开发用于在临诊前期和癌症诊断方面进行病理学解读的仪器和软件;LSBio的客户包括位于美国、欧洲和日本的超过100家制药公司。

公司介绍

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